REVERSIBLE INACTIVATION OF THE SUBSTANCE INDUCING TRANSFORMATION OF PNEUMOCOCCAL TYPES
نویسندگان
چکیده
منابع مشابه
Reversible Inactivation of the Substance Inducing Transformation of Pneumococcal Types
1. The transforming substance of Pneumococcus Type III is inactivated by treatment with ascorbic acid. This effect of ascorbic acid is catalyzed by traces of cupric ion and is prevented by the presence of sulfhydryl compounds. 2. Under certain conditions, the activity of transforming substance treated with ascorbic acid can be restored by the use of glutathione and other sulfhydryl compounds. 3...
متن کاملStudies on the Chemical Nature of the Substance Inducing Transformation of Pneumococcal Types
It has been shown that extremely minute amounts of purified preparations of desoxyribonuclease are capable of bringing about the complete and irreversible inactivation of the transforming substance of Pneumococcus Type III. The significance of the effect of the enzyme, and its bearing on the chemical nature of the transforming substance, together with certain considerations concerning the biolo...
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The development of the science of bacteriology has been marked by notable advances in the study of disease and in the control of industrial and agricultural processes in which micrc6rganisms play a vital role. For the most part, these advances arose from a study of the general properties of bacteria and of the relationship between them and their environment. In recent years, as a result of a cl...
متن کاملTechniqiye for Inducing Transformation of Pneumococcal Types in Vitro By
Griffith (1) was the first to show that S forms of pneumococci could be transformed from one specific S type into other specific S types through the intermediate stage of the R form. In recent publications by one of the authors (2, 3), Griffith's observations on the transformation of pneumococcal types were confirmed and extended. The results of these investigations m a y be summarized as follows:
متن کاملTechniqiye for Inducing Transformation of Pneumococcal Types in Vitro
Griffith (1) was the first to show that S forms of pneumococci could be transformed from one specific S type into other specific S types through the intermediate stage of the R form. In recent publications by one of the authors (2, 3), Griffith's observations on the transformation of pneumococcal types were confirmed and extended. The results of these investigations m a y be summarized as follows:
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1945
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.81.5.501